10 Best Herbicides For Centipede Grass 2026 in the United States

Ortho WeedClear Weed Killer for Lawns is a selective herbicide that effectively targets over 250 common weeds, including dandelions and clover, making it a versatile choice for lawn care. Its formula is designed to kill weeds down to the root without harming your grass, provided it is used as directed, which is critical for maintaining centipede grass.

The product is pre-mixed and comes in a ready-to-spray format, which simplifies the application process; you just need to connect it to your garden hose and spray. This ease of use is ideal for homeowners who prefer a straightforward weed control method. Additionally, it is rainproof within an hour, allowing for quick re-entry of people and pets into treated areas after the spray has dried.

While it claims to be safe for lawns when used correctly, it's important to follow the directions carefully to avoid any potential harm to centipede grass. The product's effectiveness may vary, and it may not be suitable for all types of lawns or weeds not listed on the product label. Therefore, users should check the complete weed list on the label to ensure it targets the specific weeds present in their lawn. Ortho WeedClear offers a reliable solution for weed control in lawns with centipede grass, combining ease of use and effective weed elimination, but requires careful application to ensure optimal results.

The Scotts Turf Builder Bonus S Southern Weed & Feed2 is designed for use on a variety of southern grasses including centipede grass, making it suitable for your lawn care needs. The product is selective, meaning it targets and kills specific weeds such as dollarweed, clover, and dandelion without harming your grass. It's a post-emergent herbicide, which is great for dealing with existing weeds rather than preventing new ones, and also acts as a fertilizer to promote healthy grass growth and stronger roots, potentially reducing future weed problems by crowding them out.

It is crucial to apply it to a dry lawn and water it in immediately for optimal effectiveness. Covering up to 5,000 square feet with a 17.24-pound bag, it's a good option for larger lawns. A point to consider is the active ingredient, Atrazine, which is effective but can be a concern if not used as directed, so following the application instructions carefully is advisable. Additionally, while it's effective on a variety of weeds, its selective nature means it won't work on all types of weeds. The dual function of weed control and fertilization makes it a convenient choice for maintaining a healthy lawn.

The Andersons Barricade Professional-Grade Granular Pre-Emergent Weed Control is a solid choice for those looking to prevent weeds in their centipede grass lawns. Designed as a pre-emergent herbicide, it effectively stops a variety of grassy and broadleaf weeds before they sprout, including common nuisances like crabgrass and goosegrass. This product is not intended for eliminating existing weeds, so it's best used as a preventative measure in early spring and fall.

With a coverage of up to 5,800 square feet and an active ingredient concentration of 0.48% prodiamine, it offers professional-grade weed control. The DG Pro formulation ensures even distribution and superior performance by allowing more particles per square inch. Applying it in granular form is straightforward, and it’s safe for use on centipede grass, making it suitable for homeowners and lawn care professionals alike.

However, those dealing with established weeds will need a different solution, as this product is only effective as a pre-emergent. Additionally, the 18-pound weight may be cumbersome for some users, and careful application is needed to avoid overuse. Made in the USA, this product is a trusted option in the lawn care market.